Life & Culture Medicine Blog

Scientists Redefine Alzheimer’s Disease Based On Biology

Scientists redefine Alzheimer’s disease with an aim to lessen the effects of the disease on patients, families, and society. Based on biology, researchers have proposed a new way to define Alzheimer’s disease.


The new method focuses on biological changes in the body such as rain changes, rather than memory loss and cognitive decline that are used today. The aim is to improve treatment approaches by using more objective criteria rather than treating people.

The National Institute on Aging and Alzheimer’s Association released the new research framework on Tuesday which includes diagnostic recommendations for the mild cognitive impairment, dementia stage of Alzheimer’s disease, and preclinical.

There’re around 50 million dementia suffers in the world while the Alzheimer’s is the most common cause of dementia. Women are at 16 percent higher risk of developing Alzheimer’s related diseases as compared to men who have 11 percent risk of developing the condition according to the Aging, Demographics, and Memory Study.

Moreover, according to the AA 2017 Alzheimer’s Disease Facts and Figures, one in 10 Americans ages 65 years and above found suffering from Alzheimer’s disease.

“We are proposing that the disease be defined in living people by evidence of brain pathology using biomarker studies, either brain imaging or body fluid examination and that clinical symptoms should be regarded for what they are — a product or result of the disease, as opposed to the definition of the disease,” lead author Dr. Clifford Jack, Jr. of the Mayo Clinic explained.

Presented in 2011, the new recommendations were published on April 10 in Alzheimer’s and Dementia.


Get Free Sample Copy of Report